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Articles

Last 5 years

  1. Lourenço, E. M. G.; Di Iório, J. F.; da Silva, F.; Fialho, F. L. B.; Monteiro, M. M.; Beatriz, A.; Perdomo, R. T.; Barboza, E. G.; Oses, J. P.; de Arruda, C. C. P.; de Souza, W. A. J.; Rafique, J.; de Lima, D. P. Flavonoid Derivatives as New Potent Inhibitors of Cysteine Proteases: An Important Step toward the Design of New Compounds for the Treatment of Leishmaniasis. Microorganisms 2023, 11, 225.
  2. Braga, F.; Rafique, J.; Gomes, R. S.; de Lima, D. P.; Beatriz, A. In Water Morita-Baylis-Hillman Reactions of Acrylates Enabled by Aqueous Micellar Catalysis using TPGS-750M. Sustainable Chemistry and Pharmacy, 2023, 31, 100925.
  3. Braga, F.; Ojeda, M.; Perdomo, R. T.; de Albuquerque, S.; Rafique, J.; de Lima, D. P.; Beatriz, A. Synthesis of cardanol-based 1,2,3-triazoles as potential green agents against neoplastic cells. Sustainable Chemistry and Pharmacy, 2021, 20, 100408.
  4. Vitor, N.; De Souza, A. M. ; Rafique, J.; Gomes, R. S. ; De Lima, D. P. ; Beatriz, A.  Straightforward synthesis of cytosporone analogs AMS35AA and AMS35BB.  Anais da Academia Brasileira de Ciências, 2021, 93, e20201347.
  5. Oliveira, R. J.; Cunha-Laura, A.L.; Gonçalves, C. A.; Monreal, A. C. D.; Sampaio, D.; Meza, A.; de Lima, D. P.; Beatriz, A.; Amaral, E. A.; Auharek, S. A. Effects of 3 Heptyl 3,4,6 trimethoxy 3H isobenzofuran 1 one alone or/in association with cyclophosphamide on testicular function. ANDROLOGIA, 2020.
  6. James M.Wood, Nishikant S. Satam, Renata G. Almeida, Vinicius S. Cristani, Dênis P. Lima, Luiza D. Pereira, Kelly Salomão, Rubem F. S. Menna-Barreto, Irishi N.N.Namboothiri, John F. Bower, Eufrânio N. da Silva Júnior. Strategies towards potent trypanocidal drugs: application of Rh-catalyzed [2+2+2] cycloadditions, sulfonyl phthalide annulation and nitroalkene reactions for the synthesis of substituted quinones and their evaluation against Trypanosoma cruzi. Bioorg. Med. Chem. 2020.
  7. Vaijinath Mane, Sudheesh Sivanandan, Rafael Santana, Adilson Beatriz, Eufrânio Nunes da Silva Júnior, and Irishi N. N. Namboothiri.  Synthesis of Densely Substituted Sulfonylfurans and Dihydrofurans via Cascade Reactions of α-Functionalized Nitroalkenes with β-Ketosulfones. J. Org. Chem., 2020.
  8. Rejane Gonçalves Diniz Khodyuk, Ruoli Bai, Ernest Hamel, Estela Mariana Guimarães Lourenço, Euzébio Guimarães Barbosa, Adilson Beatriz, Edson dos Anjos dos Santos, Dênis Pires de Lima. Diaryl Disulfides and Thiosulfonates as Combretastatin A-4 Analogues: Synthesis, Cytotoxicity and Antitubulin Activity. Bioorg. Chem. 2020. 
  9. dos Santos, D. S.; Meza, A.; Gomes, R. D.; de Lima, D. P.; Beatriz, A. A Straightforward Method for Synthesizing Bioactive Resorcinolic Lipid Analogues. Orbital: Electron. J. Chem. 2020.
  10. Copini, S. ; MICHELETTI, A. C. ; De Souza, A. M. ; Gomes, R. S. ; De Lima, D. P. ; BEATRIZ, A.  Synthesis and Antioxidant and Antimicrobial Properties of β-Hydroxy Sulfides, Sulfoxides, and Sulfones Derived from Cardanol and Glycerol Derivatives. J. Braz. Chem. Soc. 2020, 31, 2569-2582.
  11. NANTES, CAMILLA I. ; PEREIRA, INGRID D. ; BAI, RUOLI ; HAMEL, ERNEST ; BURNETT, JAMES C. ; OLIVEIRA, RODRIGO J. ; F. C. MATOS, MARIA ; BEATRIZ, ADILSON ; YONEKAWA, MURILO K. A. ; PERDOMO, RENATA T. ; Lima, Dênis P. ; Bogo, Danielle ; A. DOS SANTOS, EDSON . -(4-Methoxyphenyl)-4-methoxybenzenesulfonothioate as a Promising Lead Compound for the Development of a Renal Carcinoma Agent. ChemMedChem, v. 15, p. 449-458, 2020.
  12. PELIZARO, BRUNO IVO ; BRAGA, FELIPE CAMARGO ; CRISPIM, BRUNO DO AMARAL ; DE BARROS, LUIZ GUILHERME MAIOLINO LACERDA ; PESSATTO, LUCAS ROBERTO ; OLIVEIRA, EDWIN JOSÉ TORRES ; VANI, JULIANA MIRON ; DE SOUZA, ANTONIO PANCRÁCIO ; GRISOLIA, ALEXEIA BARUFATTI ; ANTONIOLLI-SILVA, ANDRÉIA CONCEIÇÃO MILAN BROCHADO ; de Lima, Dênis Pires ; DOS SANTOS JAQUES, JEANDRE AUGUSTO ; BEATRIZ, ADILSON ; OLIVEIRA, RODRIGO JULIANO . Assessment of acute toxicity and cytotoxicity of fluorescent markers produced by cardanol and glycerol, which are industrial waste, to different biological models. Environmental Science and Pollution Research, p. 1193, 2019.
  13. NARENDAR’REDDY, THATIKONDA ; BEATRIZ, ADILSON ; JAYATHIRTHA’RAO, VAIDYA ; DE’LIMA, DÊNIS PIRES . Carbonyl Compounds- Journey to Amide Bond Formation. Chemistry-An Asian Journal, v. 14, p. 344-388, 2019.
  14. JULIANO OLIVEIRA, RODRIGO ; PEREIRA, FABRÍCIA PANIAGO AJALA NERY ; SILVEIRA, INGRIDHY OSTACIANA MAIA FREITAS DA ; LIMA, RICARDO VIEIRA DE ; BERNO, CLAUDIA RODRIGUES ; PESARINI, JOÃO RENATO ; ANTONIOLLI-SILVA, ANDRÉIA CONCEIÇÃO MILAN BROCHADO ; MONREAL, ANTÔNIO CARLOS DUENHAS ; ADILSON, BEATRIZ ; LIMA, Dênis Pires de ; GOMES, ROBERTO DA SILVA . Assessment of the toxicogenic effects and cell death potential of the ester (Z)-methyl 4-((1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)amino)-4-oxobut-2-anoate in combination with cisplatin, cyclophosphamide and doxorubicin. GENETICS AND MOLECULAR BIOLOGY (ONLINE VERSION), v. 42, p. 399-410, 2019.
  15. Navarro, S. D.; Pessatto, L. R.; Meza, A.; Oliveira, E. J. T.; Auharek, S. A.; Vilela, L. C.; De Lima, D. P.;Azevedo, R. B.; Kassuya, C. A.; Caceres, O. I. A.; Gomes, R. S.; Beatriz, A.; Oliveira, R. J.; Martines, M. A. U. Resorcinolic lipid 3-heptyl-3,4,6-trimethoxy-3H-isobenzofuran-1-one is a strategy for melanoma treatment. Life Sciences 2018, 209, 300-312.
  16. Juliana Miron Vani, Maria Tereza Ferreira Duenhas Monreal, Sarah Alves Auharek, Andréa Luiza Cunha-Laura, Eduardo José de Arruda, Alessandra Ramos Lima, Cicera Maria da Silva, Andréia Conceição Milan Brochado Antoniolli-Silva, Dênis Pires de Lima, Adilson Beatriz, Rodrigo Juliano Oliveira. The mixture of cashew nut shell liquid and castor oil results in an efficient larvicide against Aedes aegypti that does not alter embryo-fetal development, reproductive performance or DNA integrity. Plos One 2018, 1-21.
  17. Rodrigo Juliano Oliveira, Naiara da Cruz Leite Santos, João Renato Pesarini, Beatriz Carneiro de Oliveira, Claudia Rodrigues Berno, Flávio Henrique Souza de Araújo, Ingridhy Ostaciana Maia Freitas da Silveira , Raquel Oliveira Nascimento , Andréia Conceição Milan Brochado Antoniolli-Silva, Antônio Carlos Duenhas Monreal, Adilson Beatriz, Dênis Pires de Lima, and Roberto da Silva Gomes. Assessment of genetic integrity, splenic phagocytosis and cell death potential of (Z)-4-((1,5-dimethyl-3-oxo-2-phenyl-2,3dihydro-1H-pyrazol-4-yl) amino)-4-oxobut-2-enoic acid and its effect when combined with commercial chemotherapeutics. Genetics and Molecular Biology Online Ahead of Print. 2018
  18. Thatikonda Narendar Reddy, Adilson Beatriz, Rosangela da Silva Lopes, Maria Rita Marques, Edson dos Anjos dos Santos, Camila Izabela Nantes, Maria de Fátima Cepa Matos, Renata Trentin Perdomo, Indiara Correia Pereira, Simone Schneider Weber, Dênis Pires de Lima. Design, synthesis and Structure-Activity Relationship of novel Phenolic based Pyrimidine hybrids from Cashew Nut Shell Liquid (CNSL) components as potential antitumor agents.  Chemical Biology Letters , 2018, 5(2), 41-54
  19. Avvari Prasad, Felipe Braga, Rosângela Lopes, Gleison Casagrande, Dênis de Lima & Adilson Beatriz. Cu(I)-phosphine complex: An efficient catalyst for synthesis of 3-indole derivatives through one-pot MCR under mild conditions. Synthetic Communications, 2018, 48, 104-114. Free eprints 
  20. Bhaskar R. Manda; Avvari N. Prasad; Narendar R. Thatikonda; Valdemar Lacerda Jr.; Layla R. Barbosa; Heloa Santos; Wanderson Romão; Fernando R. Pavan; Camila M. Ribeiro; Edson A. dos Santos; Maria R. Marques; Dênis P. de Lima; Ana C. Micheletti; Adilson Beatriz. Synthesis, Antibacterial and Antitubercular Evaluation of Cardanol and Glycerol‑Based β-Amino Alcohol Derivatives. J. Braz. Chem. Soc. 2017.
  21. de Oliveira, P. D. et al. Ozonolysis of neem oil: Preparation and characterization of potent antibacterial agents against multidrug resistant bacterial strains. RSC Advances 2017, 7, 34356-34365
  22. Braga, F. C; Avvari, N. P.; Gomes, R. S.; Nascimento, V. A.;  Oliveira, S. L.; Caires, A. R.L.; de Lima, D. P.; Beatriz, A. Design, synthesis and fluorescence analysis of potential fluorescent markers based on cardanol and glycerol.  Dyes and Pigments 2017, 141, 235-244.
  23. de Lima, D. P.; Giannesi, G.; Santos, E. A. ; Lopes, R. S.; Beatriz, A. et al. N-Acetylation of Aromatic Amines by the Soil Fungus Aspergillus japonicus (UFMS 48.136). Letters in Organic Chemistry. In Press 2017.
  24. de Araújo, F. GH. S.; de Figueiredo, D. R.; Auharek, S. A; Pesarini, J. R.; Meza, A.; Gomes, R. S.; Monreal, A. C. D.; Antoniolli-Silva, A. C. M. B.; de Lima, D. P.; Kassuya, C. A. L.; Beatriz, A.; Oliveira, R. J. In vivo Chemotherapeutic Insight of a Novel Isocoumarin (3-hexyl-5,7-dimethoxy-isochromen-1-one): Genotoxicity, cell death induction, leukometry and phagocytic evaluation. Genetics and Molecular Biology, 2017, 40, 665-675.
  25. Paiva, D. R.; De Lima, D. P.; Avvari, N. P. ; Arruda, E. J.; Cabrini, I.; Marques, M. R.; Santos, E. A.; Biaggio, F. C.; Sangi, D. P.; Beatriz, A. A potent larvicidal agent against Aedes aegypti mosquito from cardanol. Anais da Academia Brasileira de Ciências 2017, 89, 373-382.
  26. Berno, C. R.; Rós, B. T.; da Silveira, I. O. M. F.; Coelho, H. R.; Antoniolli-Silva, A. C. M. B.; Beatriz, A.; de Lima, D. P.; Monreal, A. C. D.; Sousa, F. G.; Gomes, R. S.; Oliveira, R. J. 4-Aminoantipyrine reduces toxic and genotoxic effects of doxorubicin, cisplatin, and cyclophosphamide in male mice. Mutation Research/Genetic Toxicology and Environmental Mutagenesis 2016, 805,  19–24.
  27. Schneider, B. U. C.; De Souza, A. M.; Beatriz, A.; Carvalho, P. C.; Mauro, M. O.; Karaziack, C. B.; De Lima, D. P.; Oliveira, R. J. Cardanol: toxicogenetic assessment and its effects when combined with cyclophosphamide. Genetics and Molecular Biology 2016, 39, 2, 279-289
  28. Micheletti, A. C.; Honda, N. K.; Carvalho, N. C. P.; De Lima, D. P.; Beatriz, A. Design, Synthesis and in vitro Antimicrobial Activity Evaluation of Novel Hybrids of Lichexantone-THC Derivatives. Orbital: Electron. J. Chem. 2015, 7, 301.
  29. Kogawa, N. R. A.; De Arruda, E. J.; Micheletti, A. C.; Matos, M. F. C.; De Oliveira, L. C. S.; De Lima, D. P.; Carvalho, N. C. P.; Oliveira, P. D.; Cunha, M. C.; Ojeda, M.; Beatriz, A. Synthesis, characterization, thermal behavior and biological activity of ozonides from vegetable oils. RSC Advances: an international journal to further the chemical sciences, 2015, 5, 65427 – 65436.
  30. Meza, A.; dos Santos, E. dos A.; Gomes, R. S. ; De Lima, D. P. ; Beatriz, A. Cytosporones: Isolation, Synthesis and Biological Activities of a Promising Class of Phenolic Lipids. Current Organic Synthesis, 2015, 12 (5): 618-638.
  31. Oliveira, R. J.; Navarro, S. D.; De Lima, D. P.; Meza, A.; Pesarini, J. R.; Gomes, R. S.; Karaziack, C. B.; Mauro, M. O.; Cunha-Laura, A. L.; Monreal, A. C. D.; Romão, W.; Lacerda Júnior, V.; Beatriz, A. A novel cytosporone 3-Heptyl-4,6-dihydroxy-3H-isobenzofuran-1-one: synthesis; toxicological, apoptotic and immunomodulatory properties; and potentiation of mutagenic damage. BMC Cancer, 2015, 561, 1-15.
  32. Araújo, Y. J. K.; Avvari, N. P.; Paiva, D. R.; De Lima, D. P.; Beatriz, A. Synthesis and enzymatic resolution of racemic 2,3-epoxy propyl esters obtained from glycerol. Tetrahedron Letters, 2015, 56, 1696.