Ozonolysis of neem oil: Preparation and characterization of potent antibacterial agents against multidrug resistant bacterial strains  

Paola Dias de Oliveira, Nathália Rodrigues de Almeida, Martin Conda-Sheridan, Rafael do Prado Apparecido, Ana Camila Micheletti, Nadia Cristina Pereira Carvalho, Edson dos Anjos dos Santos, Maria Rita Marques, Eduardo José de Arruda, Glaucia Braz Alcantara, Lincoln Carlos Silva de Oliveira, Dênis Pires de Lima, and Adilson Beatriz*

The aim of this work was the synthesis, characterization and evaluation of antimicrobial potential of neem ozonated oils. The products showed excellent broad-spectrum antimicrobial activity against standard E. faecalis, clinical vancomycin resistant E. faecium, clinical multiresistant K. pneumoniae (KPC), and S. aureus (MRSA and standard).

RSC  Advances – 2017 – In Press.

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