Fine Chemistry and Biotechnology
This research group was created in 2007 under the name of Glycerol Chemistry. In April 2021, the name of the research group was changed to Fine Chemistry and Biotechnology. Glycerol (and also cardanol) chemistry remains a topic of interest and is a strength of the group. Moreover, the fine chemistry sector is responsible for supplying a country with strategic products for healthcare and food safety. The group’s mission is to develop cheaper and more efficient routes for preparing synthesis intermediates, as well as active pharmaceutical ingredients (API) and agrochemicals through chemical synthesis and biotechnology. The group is focused on modernizing its laboratory infrastructure to create an ecosystem favorable to innovation in this strategic area for the country, and we seek to be a link between the university and companies interested in investing in research to make the country less dependent on imports of API and of agrochemicals.
Researchers
- Adilson Beatriz – UFMS (Group leader) – Email: adilson.beatriz@ufms.br)
- Alisson Meza de Souza – UFAM
- Ana Camila Micheletti – UFMS
- Dênis Pires de Lima – UFMS
- Felicia Megumi Ito – IFMS
- Jamal Rafique – UFMS
- Kleber Thiago de Oliveira – UFSCar
- Roberto da Silva Gomes – North Dakota State University (NDSU)
- Valdemar Lacerda Júnior – UFES
Lines of research
- Organic Synthesis
- Green and Sustainable Chemistry
Further output
Articles
- Reddy, D. S.; Reddy, G. G.; Beatriz, A.; Corey, E. J. Contrasting Diastereoselectivity between Cyclic Nitrones and Azomethine Ylides. Stereocontrolled Pathways to cis-anti-anti-cis-Oxazatetraquinanes from a Bicyclic Nitrone. Org. Lett. 2021, 23, 14, 5445–5447.
- Braga, F.; Ojeda, M.; Perdomo, R. T.; de Albuquerque, S.; Rafique, J.; de Lima, D. P.; Beatriz, A. Synthesis of cardanol-based 1,2,3-triazoles as potential green agents against neoplastic cells. Sustainable Chemistry and Pharmacy, 2021, 20, 100408.
- Vitor, N.; De Souza, A. M. ; Rafique, J.; Gomes, R. S. ; De Lima, D. P. ; Beatriz, A. Straightforward synthesis of cytosporone analogs AMS35AA and AMS35BB. Anais da Academia Brasileira de Ciências, 2021, 93, e20201347.
- Bhaskar R. Manda; Avvari N. Prasad; Narendar R. Thatikonda; Valdemar Lacerda Jr.; Layla R. Barbosa; Heloa Santos; Wanderson Romão; Fernando R. Pavan; Camila M. Ribeiro; Edson A. dos Santos; Maria R. Marques; Dênis P. de Lima; Ana C. Micheletti; Adilson Beatriz. Synthesis, Antibacterial and Antitubercular Evaluation of Cardanol and Glycerol‑Based β-Amino Alcohol Derivatives. J. Braz. Chem. Soc. 2017.
- Paiva, D. R.; De Lima, D. P.; Avvari, N. P. ; Arruda, E. J.; Cabrini, I.; Marques, M. R.; Santos, E. A.; Biaggio, F. C.; Sangi, D. P.; Beatriz, A. A potent larvicidal agent against Aedes aegypti mosquito from cardanol. Anais da Academia Brasileira de Ciências 2017, 89, 373-382.
- Braga, F. C; Avvari, N. P.; Gomes, R. S.; Nascimento, V. A.; Oliveira, S. L.; Caires, A. R.L.; de Lima, D. P.; Beatriz, A. Design, synthesis and fluorescence analysis of potential fluorescent markers based on cardanol and glycerol. Dyes and Pigments 2017, 141, 235-244.
- Araújo, Y. J. K.; Avvari, N. P.; Paiva, D. R.; De Lima, D. P.; Beatriz, A. Synthesis and enzymatic resolution of racemic 2,3-epoxy propyl esters obtained from glycerol. Tetrahedron Letters, 2015, 56, 1696.
- Beatriz, A.; Araújo, Y. K.; de Lima, D. P. Glicerol: um breve histórico e aplicação em sínteses estereosseletivas (Glycerol: a brief history and their application in stereoselective syntheses). Quim. Nova, 2011, 34, 306-319.
- Araújo, Y. J. K. ; de Lima, D. P.; BEATRIZ, A. Preliminary study on enzymatic kinetic resolution of isopropylidene glycerol. Orbital: The Electronic Journal of Chemistry, 2009, 1, 251-254, 2009.
- Pascoski, F. ; Kamiya, R. Y. ; ITO, F. M. ; MICHELETTI, A. C. ; De Souza, A. M. ; CORSINO, J. ; LIMA, Denis Pires de ; BEATRIZ, A. Produção de ácidos graxos poliinsaturados por Mucor ramosissimus usando (bio)glicerol como fonte de carbono. In: X Simpósio Brasil-Japão 2010 e III Simpósio Intercâmbio Brasil-Japão de Sustentabilidade: um desafio da humanidade, 2010, Campo Grande. Trabalhos Aprovados. São Paulo: Associação Brasil-Japão de Pesquisadores, 2010. v. PA030. p. 1.