{"id":2358,"date":"2018-03-21T09:39:37","date_gmt":"2018-03-21T13:39:37","guid":{"rendered":"https:\/\/sintmol.ufms.br\/?p=2358"},"modified":"2018-03-21T11:38:29","modified_gmt":"2018-03-21T15:38:29","slug":"accepeted-paper-plos-one-mixture-cashew-nut-shell-liquid-castor-oil-results-efficient-larvicide-aedes-aegypti","status":"publish","type":"post","link":"https:\/\/sintmol.ufms.br\/en\/accepeted-paper-plos-one-mixture-cashew-nut-shell-liquid-castor-oil-results-efficient-larvicide-aedes-aegypti\/","title":{"rendered":"Accepted paper in PLOS ONE: The mixture of cashew nut shell liquid and castor oil results in an efficient larvicide against…"},"content":{"rendered":"

\"\"<\/a>The mixture of cashew nut shell liquid and castor oil results in an efficient larvicide against Aedes aegypti<\/i> that does not alter embryo-fetal development, reproductive performance or DNA integrity<\/h2>\n

Juliana Miron Vani, <\/a>Maria Tereza Ferreira Duenhas Monreal, <\/a>Sarah Alves Auharek, <\/a>Andr\u00e9a Luiza Cunha-Laura, <\/a>Eduardo Jos\u00e9 de Arruda, <\/a>Alessandra Ramos Lima, <\/a>Cicera Maria da Silva, <\/a>Andr\u00e9ia Concei\u00e7\u00e3o Milan Brochado Antoniolli-Silva, <\/a>D\u00eanis Pires de Lima, <\/a>Adilson Beatriz* , <\/a>Rodrigo Juliano Oliveira*<\/a><\/p>\n

Abstract<\/h2>\n

Dengue fever, chikungunya fever and Zika virus are epidemics in Brazil that are transmitted by mosquitoes, such as Aedes aegypti<\/em> or Aedes albopictus<\/em>. The liquid from shells of cashew nuts is attractive for its important biological and therapeutic activities, which include toxicity to mosquitoes of the genus Aedes<\/em>. The present study evaluated the effects of a mixture of surfactants from natural cashew nutshell liquid and castor oil (named TaLCC-20) on the mortality of larvae and on the reproductive performance, embryonic and fetal development and genetic stability of Swiss mice. A total of 400 Ae<\/em>. aegypti<\/em> larvae (third larval stage) were treated with TaLCC-20 concentrations of 0.05 mg\/L, 0.5 mg\/L, or 5 mg\/L (ppm). Twenty pregnant female mice were also orally administered TaLCC-20 at doses of 5 mg\/kg and 50 mg\/kg body weight (b.w.), and 10 animals were given only drinking water at 0.1 mL\/10 g b.w. (orally). The results of a larvicide test demonstrated that 5 mg\/mL TaLCC-20 killed 100% of larvae within three hours, which is comparable to the gold standard indicated by the Ministry of Health. Overall, these results show that TaLCC-20 is an efficient larvicide that does not induce genetic damage. In addition, changes in reproductive performance and embryo-fetal development appear positive, and the formulation is cost effective. Therefore, TaLCC-20 is an important product in the exploration of natural larvicides and can assist in fighting mosquitos as vectors for dengue fever, chikungunya fever and Zika virus, which are emerging\/re-emerging and require proper management to ensure minimal harm to the human population. Therefore, TaLCC-20 can be considered a key alternative to commercial products, which are effective yet toxigenic.<\/p>\n

PLOS ONE: Published: March 19, 2018. https:\/\/doi.org\/10.1371\/journal.pone.0193509<\/a><\/p>\n

Related Images:<\/h3>","protected":false},"excerpt":{"rendered":"

The mixture of cashew nut shell liquid and castor oil results in an efficient larvicide against Aedes aegypti that does not alter embryo-fetal development, reproductive performance or DNA integrity Juliana Miron Vani, Maria Tereza Ferreira Duenhas Monreal, Sarah Alves Auharek, Andr\u00e9a Luiza Cunha-Laura, Eduardo Jos\u00e9 de Arruda, Alessandra Ramos Lima, Cicera Maria da Silva, Andr\u00e9ia Concei\u00e7\u00e3o Milan Brochado Antoniolli-Silva, D\u00eanis Pires de Lima, Adilson Beatriz* , Rodrigo […]<\/p>\n","protected":false},"author":126,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"ngg_post_thumbnail":0,"footnotes":""},"categories":[3],"tags":[],"coauthors":[],"class_list":["post-2358","post","type-post","status-publish","format-standard","hentry","category-fotos-imagens"],"_links":{"self":[{"href":"https:\/\/sintmol.ufms.br\/en\/wp-json\/wp\/v2\/posts\/2358","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/sintmol.ufms.br\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/sintmol.ufms.br\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/sintmol.ufms.br\/en\/wp-json\/wp\/v2\/users\/126"}],"replies":[{"embeddable":true,"href":"https:\/\/sintmol.ufms.br\/en\/wp-json\/wp\/v2\/comments?post=2358"}],"version-history":[{"count":4,"href":"https:\/\/sintmol.ufms.br\/en\/wp-json\/wp\/v2\/posts\/2358\/revisions"}],"predecessor-version":[{"id":2362,"href":"https:\/\/sintmol.ufms.br\/en\/wp-json\/wp\/v2\/posts\/2358\/revisions\/2362"}],"wp:attachment":[{"href":"https:\/\/sintmol.ufms.br\/en\/wp-json\/wp\/v2\/media?parent=2358"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/sintmol.ufms.br\/en\/wp-json\/wp\/v2\/categories?post=2358"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/sintmol.ufms.br\/en\/wp-json\/wp\/v2\/tags?post=2358"},{"taxonomy":"author","embeddable":true,"href":"https:\/\/sintmol.ufms.br\/en\/wp-json\/wp\/v2\/coauthors?post=2358"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}