{"id":3285,"date":"2022-01-14T20:19:51","date_gmt":"2022-01-15T00:19:51","guid":{"rendered":"https:\/\/sintmol.ufms.br\/?page_id=3285"},"modified":"2022-02-11T15:07:13","modified_gmt":"2022-02-11T19:07:13","slug":"antibiotic-production","status":"publish","type":"page","link":"https:\/\/sintmol.ufms.br\/en\/research-and-development\/labbio\/antibiotic-production\/","title":{"rendered":"Production of antibiotics"},"content":{"rendered":"

\"\"<\/a>Antibiotic production by microorganisms is one of their more interesting features, particularly from a medical and commercial point of view. Penicillins and cephalosporins belong to the class of drugs known as \u03b2-lactams. Naturally produced penicillins by Penicillium chrysogenum<\/em> are classified as 1st<\/sup> generation. The 2nd<\/sup>, 3rd<\/sup> and 4th<\/sup> generations are all semi-synthetic obtained from chemical synthesis starting from 6-APA. The cephalosporins in clinical use are semi-synthetic derivatives of 7-ACA, obtained from cephalosporin C, produced by Acremonium chrysogenum<\/em>. Semi-synthetic penicillins and cephalosporins continue to interest many research groups to discover new antibiotics that may tackle super bacteria. 6-APA and 7-ACA are essential starting materials used in studies on the synthesis of the \u03b2-lactams drugs. We are interested in producing 6-APA and 7-ACA by biotechnological processes.<\/p>\n

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Antibiotic production by microorganisms is one of their more interesting features, particularly from a medical and commercial point of view. Penicillins and cephalosporins belong to the class of drugs known as \u03b2-lactams. Naturally produced penicillins by Penicillium chrysogenum are classified as 1st generation. The 2nd, 3rd and 4th generations are all semi-synthetic obtained from chemical synthesis starting […]<\/p>\n","protected":false},"author":126,"featured_media":0,"parent":639,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"ngg_post_thumbnail":0,"footnotes":""},"coauthors":[],"class_list":["post-3285","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/sintmol.ufms.br\/en\/wp-json\/wp\/v2\/pages\/3285","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/sintmol.ufms.br\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/sintmol.ufms.br\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/sintmol.ufms.br\/en\/wp-json\/wp\/v2\/users\/126"}],"replies":[{"embeddable":true,"href":"https:\/\/sintmol.ufms.br\/en\/wp-json\/wp\/v2\/comments?post=3285"}],"version-history":[{"count":20,"href":"https:\/\/sintmol.ufms.br\/en\/wp-json\/wp\/v2\/pages\/3285\/revisions"}],"predecessor-version":[{"id":3478,"href":"https:\/\/sintmol.ufms.br\/en\/wp-json\/wp\/v2\/pages\/3285\/revisions\/3478"}],"up":[{"embeddable":true,"href":"https:\/\/sintmol.ufms.br\/en\/wp-json\/wp\/v2\/pages\/639"}],"wp:attachment":[{"href":"https:\/\/sintmol.ufms.br\/en\/wp-json\/wp\/v2\/media?parent=3285"}],"wp:term":[{"taxonomy":"author","embeddable":true,"href":"https:\/\/sintmol.ufms.br\/en\/wp-json\/wp\/v2\/coauthors?post=3285"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}