{"id":1675,"date":"2017-05-27T12:23:47","date_gmt":"2017-05-27T16:23:47","guid":{"rendered":"http:\/\/sintmol.draconis.ufms.br\/?page_id=1675"},"modified":"2026-05-12T09:30:27","modified_gmt":"2026-05-12T13:30:27","slug":"projeto-tematico-i","status":"publish","type":"page","link":"https:\/\/sintmol.ufms.br\/en\/research-and-development\/projeto-tematico-i\/","title":{"rendered":"Umbrella Project I"},"content":{"rendered":"<h3 style=\"text-align: center\">Cardanol and Glycerol Exploitation<\/h3>\n<p>&nbsp;<\/p>\n<p style=\"text-align: justify\"><strong>Cardanol<\/strong> is the main constituent of <em>Cashew Nut Shell Liquid<\/em><em> (<\/em>CNSL) that represents one of major source of natural phenolic lipids. Depending on the extraction method, CNSL is classified in two types: CNSL extracted with solvent and technical CNSL. The former has mainly anacardic acid, cardol and, traces of methyl cardol. After the cashew nut being submitted to industrial process of heating, the anacardic acid is decarboxylated rendering technical CNSL which is free of anacardic acid, having as the main constituents cardanol (60-65%), cardol (15-20%) and, polymeric materials (10%). Each phenolic constituent is a mixture of saturated, monoene, diene and, triene compounds. Due to unique characteristics of cardanol and its derivatives, they have been stimulating researchers to study their potential to prepare varnish, coating materials and, as starting material for organic synthesis. The literature has focused to the preparation of hybrid molecular systems where cardanol is involved on the planning of new molecular entities.<\/p>\n<p style=\"text-align: justify\">Currently, another important industrial residue is <strong>glycerol<\/strong>. Its use in the synthesis of higher value chemicals has been highlighted in the green chemistry area for the last few years. The exponential growth of biodiesel production, in which glycerol is generated as by-product raised an enormous concern about its environmental impact. In fact, the glycerol disposal is a major issue in the mass production of biodiesel and it is desirable to find alternatives for the consumption of extra volume of crude glycerol.&nbsp;Thus, glycerol has been used as a versatile primary chemical building block to produce a great variety of commercially valuable compounds.<\/p>\n<p style=\"text-align: justify\">Taking into account the characteristics of the compounds mentioned above, we aim to combine their properties into single compounds with unique potentials.<\/p>\n<p style=\"text-align: justify\">&nbsp;<\/p>\n<p style=\"text-align: justify\"><a href=\"http:\/\/sintmol.draconis.ufms.br\/files\/2012\/11\/Captura-de-tela-2017-02-27-19.00.09.png\"><img decoding=\"async\" class=\"wp-image-1562 aligncenter\" src=\"http:\/\/sintmol.draconis.ufms.br\/files\/2012\/11\/Captura-de-tela-2017-02-27-19.00.09.png\" alt=\"Captura de tela 2017-02-27 19.00.09\" width=\"687\" height=\"359\" \/><\/a><\/p>\n<p style=\"text-align: justify\">&nbsp;<\/p>\n<hr \/>\n<h3 style=\"text-align: left\"><strong>Ongoing projects<\/strong><\/h3>\n<h5 style=\"text-align: center\"><em>1. Design and synthesis of fluorescent markers for fuels<\/em><\/h5>\n<p>&nbsp;<\/p>\n<p><a href=\"http:\/\/sintmol.draconis.ufms.br\/files\/2017\/02\/DP_Felipe.png\"><img decoding=\"async\" class=\"wp-image-1517 size-full aligncenter\" src=\"http:\/\/sintmol.draconis.ufms.br\/files\/2017\/02\/DP_Felipe.png\" alt=\"D&amp;P_Felipe\" width=\"515\" height=\"138\" srcset=\"https:\/\/sintmol.ufms.br\/files\/2017\/02\/DP_Felipe.png 515w, https:\/\/sintmol.ufms.br\/files\/2017\/02\/DP_Felipe-150x40.png 150w, https:\/\/sintmol.ufms.br\/files\/2017\/02\/DP_Felipe-300x80.png 300w\" sizes=\"(max-width: 515px) 100vw, 515px\" \/><\/a><\/p>\n<hr \/>\n<h5 style=\"text-align: center\"><em>2. Design and synthesis of new surfactants for micellar catalysis \u2013 Nanoreactors<\/em><\/h5>\n<p>&nbsp;<\/p>\n<p><a href=\"http:\/\/sintmol.ufms.br\/files\/2017\/05\/nanoreactor.png\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-2214\" src=\"http:\/\/sintmol.draconis.ufms.br\/files\/2017\/05\/nanoreactor-1024x307.png\" alt=\"\" width=\"584\" height=\"175\" \/><\/a><\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p><a href=\"http:\/\/sintmol.ufms.br\/files\/2020\/10\/micela.png\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-2889 aligncenter\" src=\"http:\/\/sintmol.ufms.br\/files\/2020\/10\/micela-300x218.png\" alt=\"\" width=\"472\" height=\"343\" srcset=\"https:\/\/sintmol.ufms.br\/files\/2020\/10\/micela-300x218.png 300w, https:\/\/sintmol.ufms.br\/files\/2020\/10\/micela-150x109.png 150w, https:\/\/sintmol.ufms.br\/files\/2020\/10\/micela-441x320.png 441w, https:\/\/sintmol.ufms.br\/files\/2020\/10\/micela.png 508w\" sizes=\"(max-width: 472px) 100vw, 472px\" \/><\/a><\/p>\n<p><a href=\"http:\/\/sintmol.ufms.br\/files\/2012\/11\/Captura-de-tela-2017-02-25-00.46.44.png\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-1559 aligncenter\" src=\"http:\/\/sintmol.ufms.br\/files\/2012\/11\/Captura-de-tela-2017-02-25-00.46.44.png\" alt=\"\" width=\"469\" height=\"332\" \/><\/a><\/p>\n<p style=\"text-align: center\">This&nbsp;project has been inspired by work of the&nbsp;<strong><a href=\"http:\/\/www.chem.ucsb.edu\/lipshutzgroup\/research\" target=\"_blank\" rel=\"noopener noreferrer\">Lipshutz Research Group<\/a><\/strong>, University of California, Santa Barbara.<\/p>\n<hr \/>\n<h5 style=\"text-align: center\">&nbsp;<\/h5>\n<h5 style=\"text-align: center\">&nbsp;<\/h5>\n<h5 style=\"text-align: center\"><em>3. New nonionic amphiphiles to combat the Aedes aegypti mosquito and pathogenic microorganisms<\/em><\/h5>\n<p>&nbsp;<\/p>\n<p><a href=\"http:\/\/sintmol.ufms.br\/files\/2012\/11\/surfactantes.png\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-1554 size-full\" src=\"http:\/\/sintmol.draconis.ufms.br\/files\/2012\/11\/surfactantes.png\" alt=\"surfactantes\" width=\"523\" height=\"397\" \/><\/a><\/p>\n<hr \/>\n<p><strong>Selected Publications<\/strong><\/p>\n<ul>\n<li>Braga, F.; Ojeda, M.; Perdomo, R. T.; de Albuquerque, S.; Rafique, J.; de Lima, D. P.; Beatriz, A. <a href=\"https:\/\/doi.org\/10.1016\/j.scp.2021.100408\" target=\"_blank\" rel=\"noopener noreferrer\">Synthesis of cardanol-based 1,2,3-triazoles as potential green agents against neoplastic cells. <em>Sustainable Chemistry and Pharmacy<\/em>, <strong>2021, <\/strong><em>20<\/em>, 100408.<\/a><\/li>\n<li>Copini, S. ;&nbsp;MICHELETTI, A. C.&nbsp;;&nbsp;De Souza, A. M.&nbsp;;&nbsp;Gomes, R. S.&nbsp;;&nbsp;De Lima, D. P.&nbsp;;&nbsp;BEATRIZ, A.&nbsp; <a href=\"https:\/\/dx.doi.org\/10.21577\/0103-5053.20200136\" target=\"_blank\" rel=\"noopener noreferrer\">Synthesis and Antioxidant and Antimicrobial Properties of \u03b2-Hydroxy Sulfides, Sulfoxides, and Sulfones Derived from Cardanol and Glycerol Derivatives. <em>J. Braz. Chem. So<\/em>c. <strong>2020<\/strong>, <em>31<\/em>, 2569-2582.<\/a><\/li>\n<li style=\"text-align: justify\">Paiva, D. R.; De Lima, D. P.; Avvari, N. P. ; Arruda, E. J.; Cabrini, I.; Marques, M. R.; Santos, E. A.; Biaggio, F. C.; Sangi, D. P.; Beatriz, A.&nbsp;<a href=\"http:\/\/dx.doi.org\/10.1590\/0001-3765201720160615\" target=\"_blank\" rel=\"noopener noreferrer\"><strong>A potent larvicidal agent against&nbsp;<em>Aedes aegypti<\/em>&nbsp;mosquito from cardanol<\/strong><\/a>. <em>Annals of the Brazilian Academy of Sciences&nbsp;<\/em>2017, 89, 373-382.<\/li>\n<li style=\"text-align: justify\">Manda, B. R; Avvari, N. P. et al.&nbsp;<strong><a class=\"tituloArtigo\" href=\"http:\/\/dx.doi.org\/10.21577\/0103-5053.20170178\" target=\"_blank\" rel=\"noopener noreferrer\">Synthesis, Antibacterial and Antitubercular Evaluation of Cardanol and Glycerol\u2011Based \u03b2-Amino Alcohol Derivatives<\/a>.<\/strong>&nbsp;<em>J. Braz. Chem. Soc.<\/em>&nbsp;<strong>2017.<\/strong><\/li>\n<li style=\"text-align: justify\">Braga,&nbsp;F. C;&nbsp;Avvari, N. P.;&nbsp;Gomes,&nbsp;R. S.;&nbsp;Nascimento,&nbsp;V. A.;&nbsp; Oliveira, S. L.; Caires, A. R.L.; de Lima, D. P.; Beatriz, A.&nbsp;<strong><a href=\"http:\/\/dx.doi.org\/10.1016\/j.dyepig.2017.02.032\" target=\"_blank\" rel=\"noopener noreferrer\">Design, synthesis and fluorescence analysis of potential fluorescent markers based on cardanol and glycerol.&nbsp;<\/a>&nbsp;<\/strong><em>Dyes and Pigments<\/em>&nbsp;2017,&nbsp;<em>141<\/em>, 235-244.<\/li>\n<li style=\"text-align: justify\">Beatriz, A. et al. Processo de S\u00edntese de um Composto Iodado e Uso de Outros Derivados do Cardanol como Larvicidas para Controle Populacional do Mosquisto <em>Aedes aegypti<\/em> e outros Culic\u00eddeos. Patent Nr.&nbsp;BR 10 2017 024441 5.<\/li>\n<li style=\"text-align: justify\">Schneider, B. U. C.; De Souza, A. M.; Beatriz, A.; Carvalho, P. C.; Mauro, M. O.; Karaziack, C. B.; De Lima, D. P.;&nbsp;Oliveira, R. J.&nbsp;<strong><a href=\"http:\/\/dx.doi.org\/10.1590\/1678-4685-GMB-2015-0170\" target=\"_blank\" rel=\"noopener noreferrer\">Cardanol: toxicogenetic assessment and its effects when combined with cyclophosphamide<\/a>.&nbsp;<\/strong><em>Genetics and Molecular Biology<\/em>&nbsp;<strong>2016<\/strong>,&nbsp;39, 2, 279-289.<\/li>\n<li style=\"text-align: justify\">Beatriz, A. et al. <strong><a href=\"http:\/\/sintmol.draconis.ufms.br\/files\/2012\/11\/Publica%C3%A7%C3%A3o-Patente_INPI.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Processo Eficiente de Purifica\u00e7\u00e3o do Cardanol Isolado do L\u00edquido da Casca da Castanha de Caju (LCC) e Produ\u00e7\u00e3o de Derivados de Interesse industrial. Patent Nr. BR 1020140300023<\/a><\/strong><\/li>\n<\/ul>\n\n<h3>Related Images:<\/h3>","protected":false},"excerpt":{"rendered":"<p>Cardanol and Glycerol Exploitation &nbsp; Cardanol is the main constituent of Cashew Nut Shell Liquid (CNSL) that represents one of major source of natural phenolic lipids. Depending on the extraction method, CNSL is classified in two types: CNSL extracted with solvent and technical CNSL. The former has mainly anacardic acid, cardol and, traces of methyl [&hellip;]<\/p>\n","protected":false},"author":126,"featured_media":0,"parent":3315,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"ngg_post_thumbnail":0,"footnotes":""},"coauthors":[19],"class_list":["post-1675","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/sintmol.ufms.br\/en\/wp-json\/wp\/v2\/pages\/1675","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/sintmol.ufms.br\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/sintmol.ufms.br\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/sintmol.ufms.br\/en\/wp-json\/wp\/v2\/users\/126"}],"replies":[{"embeddable":true,"href":"https:\/\/sintmol.ufms.br\/en\/wp-json\/wp\/v2\/comments?post=1675"}],"version-history":[{"count":66,"href":"https:\/\/sintmol.ufms.br\/en\/wp-json\/wp\/v2\/pages\/1675\/revisions"}],"predecessor-version":[{"id":4361,"href":"https:\/\/sintmol.ufms.br\/en\/wp-json\/wp\/v2\/pages\/1675\/revisions\/4361"}],"up":[{"embeddable":true,"href":"https:\/\/sintmol.ufms.br\/en\/wp-json\/wp\/v2\/pages\/3315"}],"wp:attachment":[{"href":"https:\/\/sintmol.ufms.br\/en\/wp-json\/wp\/v2\/media?parent=1675"}],"wp:term":[{"taxonomy":"author","embeddable":true,"href":"https:\/\/sintmol.ufms.br\/en\/wp-json\/wp\/v2\/coauthors?post=1675"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}